VINCE ERECTA ЎСИМЛИК ТУРИДАН АЖРАТИБ ОЛИНГАН КОПСИНИН ВА N1-АЦЕТИЛ КОПСИНИН АЛКАЛОИДЛАРИНИ АОРТА СИЛЛИҚ МУСКУЛИНИНГ САРКОПЛАЗМАТИК РЕТИКУЛУМ Са2+-ТАШИШ ТИЗИМЛАРИГА ТАЪСИРИ
Abstract
Мақолада Vince erecta Regel ўсимлик туридан ажратиб олинган индол алкалоидларининг фармокалогик фаоллигини тахлили бўйича маълумотлар келтирилган.
Калит сўзлар: Саркоплпзматик ретикулум, инозитол–1,4,5–трифосфат, рианодин рецептори, силлиқ мускул, Са2+ ионлари, қисқариш кучи.
References
1. Zhang D. Hydroperoxide–induced oxidative stress in the arterial wall: Pharmacological characterization of the effects on arterial contractility // Dissertation. – Der Fakultät für Chemie und Pharmazie der Eberhard–Karls–Universität Tübingen zur Erlangung des Grades eines doktors. – 2007. – P.110.
2. Vandier С., Le Guennec J.Y., Bedfer G. What are the signaling pathways used by norepinephrine to contract the artery? A demonstration using guinea pig aortic ring segments // Adv. Physiol. Educ. – 2002. – V.26. – P.195–203.
3. Лакин Г.Ф. Биометрия // Москва. – Изд – во «Высшая школа». – 1990. – С.23–284.
4. Mak D.O., McBride S., Foskett J.K. Inositol 1,4,5-trisphosphate activation of inositol trisphosphate receptor Ca2+ channel by ligand tuning of Ca2+ inhibition // Proc. Natl. Acad. Sci. USA. –1998. –V. 95. –P. 15821-15825.
5. Webb C. Smooth muscle contraction and relaxantion // Advan. Physiol. Edu. –2003. –V. 27. –P. 201-206.
6. Wu K.D., Lee W.S., Wey J., Bungard D., Lytton J. Localization and quantification of endoplasmic reticulum Ca2+-ATPase isoform transcripts // Am. J. Physiol. Cell. Physiol. –1995. –V. 269. –P. 775-784.
7. Floyd R., Wray S. Calcium transporters and signalling in smooth muscles // Cell Calcium. – 2007. – V.42(45). – P. 467-476.
8. Nobel D., Borisova L., Wray S., Burdyga T. Store-operated Ca2+ entry and depolarization explain the anomalous behaviour of myometrial SR: Effects of SERCA inhibition on electrical activity, Ca2+ and force // Cell Calcium. – 2014. – V.56(3). – P. 188-194.
